Inositol is a dietary supplement that exists in the two forms of myo-inositol (MI) and d-chiro-inositol (DCI) (so called stereoisomers of inositol). Inositol has proven therapeutic activity in PCOS: Both forms have insulin-sensitizing activity, and Myo-inositol (MI) also has an effect on FSH signaling.
- Roseff S. et al. Inositol Treatment for PCOS Should Be Science-Based and Not Arbitrary. Int J Endocrinol. 2020; 2020: 6461254. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140126/
- Facchinetti F. et al. Inositols in Polycystic Ovary Syndrome: An Overview on the Advances. Trends in Endocrinology and Metabolism, Review. 2020; 31(6): 435 – 447. https://pubmed.ncbi.nlm.nih.gov/32396844/
- Unfer V. et al. Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials. Endocr Connect. 2017 Nov; 6(8): 647–658. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655679/