Long-Term Complications - PERLA Health

Long-Term Complications

Long-Term complications are consequences of a disease that can appear over time or at a later time, sometimes even after years. For PCOS, long-term complications can include metabolic disease (glucose intolerance, type 2 diabetes or dyslipidemia), cardiovascular disease, and endometrial cancer. It is important to discuss long-term complications and risks with your healthcare provider, and schedule regular preventive appointments to monitor them.


  1. Peigné M. et al. Long term complications of polycystic ovary syndrome (PCOS). Ann Endocrinol (Paris). 2014 Sep;75(4):194-9. https://pubmed.ncbi.nlm.nih.gov/25156132/
  2. Rizzo M. et al. Long-term consequences of polycystic ovary syndrome on cardiovascular risk. Fertility and Sterility, Short Communication. 2009: 91(4) Suppl. p. 1563 – 1567. https://www.fertstert.org/article/S0015-0282(08)04099-5/fulltext
  3. Kelly C.J.G. et al. The long term health consequences of polycystic ovary syndrome. British Journal of Obstetrics and Gynaecology. 2000: 197. p.1327-1338. https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/j.1471-0528.2000.tb11644.x

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