The gonadotropin-releasing hormone (GnRH) is produced by neurons in the hypothalamus. It is sent to the pituitary gland, a pea-sized gland in the brain, which as a response produces the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LH and FSH have an effect on reproductive functions such as the ovulation. Studies have shown that in patients with PCOS, GnRH secretion is relatively fast, leading to abnormal patterns of LH and FSH release.
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- Welt C.K. Physiology of gonadotropin-releasing hormone. UpToDate. https://www.uptodate.com/contents/physiology-of-gonadotropin-releasing-hormone (accessed 3. August 2020)
- University of Virginia. Causes of PCOS. https://med.virginia.edu/research-in-reproduction/patient-information/causes-of-pcos/ (accessed 3. August 2020)